Design, Resilience, Regeneration, Systems: A MOOC series about creating positive impact in complex systems as part of learning communities: This innovative Massive Open Online Course (MOOC) series, offered for free by ETH Zurich through edX, hybridizes sustainability science, systemic design and transformative action. It provides you with worldviews, tools, illustrations and transformative networks to build your capacities and engage in systemic innovation of complex systems. MVI contributes substantially to this MOOC with real-world design interventions. Out of the MOOC series of four, MOOC#1 just closed its first iteration on July 31st, with almost 2500 participants from 99 nations. MOOC#2 is scheduled to start around October 2022.